Article
Differential recognition of a tyrosine-dependent signal in the basolateral and endocytic pathways of thyroid epithelial cells.
Endocrinology - 1 Apr 2002
Lipardi Concetta, Ruggiano Germana, Perrone Lorena, Paladino Simona, Monlauzeur Laure, Nitsch Lucio, Le Bivic André, Zurzolo Chiara
Abstract excerpt
Trafficking of receptors is of crucial importance for the physiology of most exocrine and endocrine organs. It is not known yet if the same mechanisms are used for sorting in the exocytic and endocytic pathways in the different epithelial tissues. In this work, we have used a deletion mutant of the human neurotrophin receptor p75(hNTR) that is normally localized on the apical membrane when expressed in...
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