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Article

Negative regulation of dopamine transporter endocytosis by membrane-proximal N-terminal residues.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 4 Feb 2009

Sorkina Tatiana, Richards Toni L, Rao Anjali, Zahniser Nancy R, Sorkin Alexander

Abstract excerpt

The plasma membrane dopamine transporter (DAT) takes extracellular dopamine back up into dopaminergic neurons. Although the number of DATs at the cell surface is regulated by endocytosis and recycling, the molecular mechanisms that control this endocytic trafficking of DAT are not defined. To map the sequence motifs that are involved in constitutive DAT endocytosis, mutagenesis of human DAT tagged with yellow...

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Identifiers

PMID: 19193883
DOI: 10.1523/JNEUROSCI.3250-08.2009
PMCID: PMC2745124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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