Article
Experimental autoallergic sialadenitis in the LEW rat. I. Parameters of disease induction.
Cellular immunology - 1 Jul 1991
Cutler L S, Rozenski D, Coolens J, Rozing J, Angelillo M, Wayne A L, Fitzgerald K M, Greiner D L
Abstract excerpt
Experimental autoallergic sialadenitis (EAS) is an autoimmune mononuclear cell infiltration of the submandibular salivary gland that results in tissue destruction and glandular dysfunction. A previous report has described an animal model of induced EAS in LEW rats following sensitization with allogeneic WF submandibular gland (SMG). The present study extends this observation to an EAS disease model induced...
Topics
- Animals
- Antigens, CD
- Autoantibodies
- Autoimmune Diseases
- Phenotype
- Rats
- Rats, Inbred Lew
- Sialadenitis
- Submandibular Gland
