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Article

Primary sources and immunological prerequisites for sST2 secretion in humans

2 Apr 2010

Abstract excerpt

AIMS: Serum levels of the soluble growth stimulation gene-2 (sST2) are elevated in heart and pulmonary diseases. However, the relationship of the sST2/interleukin (IL)-33 axis and its triggers as well as its organ distribution is still not known. This study was thus designed to investigate the cellular origin and regulation of sST2 and IL-33 in vitro and in vivo. METHODS AND RESULTS: sST2 and IL-33 gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20363761
DOI: 10.1093/cvr/cvq104

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