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Article

Growth stimulation expressed gene 2 (ST2): Clinical research and application in the cardiovascular related diseases

4 Nov 2022

Abstract excerpt

As an interleukin (IL)-1 receptor family member, scientists found that when circulating soluble growth stimulation expressed gene 2 (sST2) is low, its ligand, IL-33, will bind to ST2L to exert protective effects on various types of cells. On the other hand, competitive binding of IL-33 occurs when sST2 concentrations are increased, followed by a reduction in the amount available for cell protection. Based on this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36407452
DOI: 10.3389/fcvm.2022.1007450

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