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Article

Cocaine and amphetamine regulated transcript (CART) gene in the comorbidity of schizophrenia with alcohol use disorders and nicotine dependence.

Progress in neuro-psychopharmacology & biological psychiatry - 16 Aug 2010

Busto Amaya, Souza Renan P, Lobo Daniela S S, Shaikh Sajid A, Zawertailo Laurie A, Busto Usoa E, Kennedy James L

Abstract excerpt

Studies have shown a genetic susceptibility to develop schizophrenia, alcohol use disorders and nicotine dependence. Brain areas related to reward and reinforcement show high expression of the cocaine and amphetamine regulated transcript (CART). Nicotine and alcohol are also able to modulate CART expression in the hypothalamic areas. In this study, we evaluated whether CART variants would influence the...

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Identifiers

PMID: 20362026
DOI: 10.1016/j.pnpbp.2010.03.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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