Molecular response prediction in gastrointestinal stromal tumors.

Abstract excerpt

Gastrointestinal stromal tumors (GISTs) are rare tumors of mesenchymal origin that develop along the gastrointestinal tract. Over ten years ago, their management dramatically changed following the discovery of an activating mutation of the KIT oncogene, which led to the use of small molecule inhibitors to therapeutically target these mutant kinases. Patients with advanced GIST, who were once a subset of sarcoma...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Benzamides
• Share to Gastrointestinal Stromal Tumors
• Share to Imatinib Mesylate