Article
Gastrointestinal stromal tumors II: medical oncology and tumor response assessment.
Seminars in oncology - 1 Aug 2009
Benjamin Robert S, Debiec-Rychter Maria, Le Cesne Axel, Sleijfer Stefan, Demetri George D, Joensuu Heikki, Schöffski Patrick, Poveda Andrés
Abstract excerpt
The finding of mutations of KIT in gastrointestinal stromal tumors (GISTs) and subsequent development of kinase-directed therapy in metastatic GIST serve as a touchstone for the translation of laboratory research into clinical therapeutics. A variety of novel developments have followed the discov...
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