Article
Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe.
European journal of human genetics : EJHG - 1 Aug 2010
Evseeva Irina, Nicodemus Kristin K, Bonilla Carolina, Tonks Susan, Bodmer Walter F
Abstract excerpt
The HLA region on chromosome 6 is gene-rich and under selective pressure because of the high proportion of immunity-related genes. Linkage disequilibrium (LD) patterns and allele frequencies in this region are highly differentiated across broad geographical populations, making it a region of inte...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
