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Article

Stabilization of G domain conformations in the tRNA-modifying MnmE-GidA complex observed with double electron electron resonance spectroscopy.

The Journal of biological chemistry - 28 May 2010

Böhme Sabine, Meyer Simon, Krüger André, Steinhoff Heinz-Jürgen, Wittinghofer Alfred, Klare Johann P

Abstract excerpt

MnmE is a GTP-binding protein conserved between bacteria and eukarya. It is a dimeric three-domain protein where the two G domains have to approach each other for activation of the potassium-stimulated GTPase reaction. Together with GidA, in a heterotetrameric alpha(2)beta(2) complex, it is involved in the modification of the wobble uridine base U34 of the first anticodon position of particular tRNAs. Here we...

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Identifiers

PMID: 20353943
DOI: 10.1074/jbc.M109.096131
PMCID: PMC2878087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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