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Transdifferentiation of adipose-derived stem cells into hepatocytes: a new approach

26 Mar 2010

Abstract excerpt

BACKGROUND: Several studies have demonstrated techniques in differentiating human adipose-derived stem cells (hADSCs) into hepatocytes. Unfortunately, transdifferentiation is inefficient, and the function of these induced hepatocyte-like cells (which we termed 'iHeps') is low compared with that of real hepatocytes. AIMS: We aimed to identify transcriptional deficiencies in iHeps that are critical to hepatocyte...

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PMID: 20353420
DOI: 10.1111/j.1478-3231.2010.02231.x

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