Article
Molecular mechanisms underlying human adipose tissue-derived stromal cells differentiation into a hepatocyte-like phenotype.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Dec 2010
Saulnier Nathalie, Piscaglia Anna Chiara, Puglisi Maria Ausiliatrice, Barba Marta, Arena Vincenzo, Pani Giovambattista, Alfieri Sergio, Gasbarrini Antonio
Abstract excerpt
BACKGROUND: Adipose tissue-derived stromal cells (ATSCs) hold great promises in regenerative medicine. In the last decade, several studies have reported the plasticity of ATSCs toward a hepatocyte-like phenotype. Nonetheless, the molecular mechanisms underlying the conversion from a mesenchymal to an epithelial phenotype remain poorly understood. AIM: In this study, we compared the full genome expression profiles...
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