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Article

Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development.

PloS one - 24 Mar 2010

Campos Yvan, Qiu Xiaohui, Zanoteli Edmar, Moshiach Simon, Vergani Naja, Bongiovanni Antonella, Harris A John, d'Azzo Alessandra

Abstract excerpt

Muscle contractile proteins are expressed as a series of developmental isoforms that are in constant dynamic remodeling during embryogenesis, but how obsolete molecules are recognized and removed is not known. Ozz is a developmentally regulated protein that functions as the adaptor component of a RING-type ubiquitin ligase complex specific to striated muscle. Ozz(-/-) mutants exhibit defects in myofibrillogenesis...

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Identifiers

PMID: 20352047
DOI: 10.1371/journal.pone.0009866
PMCID: PMC2844429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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