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Article

Degradation of the Saccharomyces cerevisiae mating-type regulator alpha1: genetic dissection of cis-determinants and trans-acting pathways.

Genetics - 1 Jun 2010

Nixon Christina E, Wilcox Alexander J, Laney Jeffrey D

Abstract excerpt

Mating phenotype in the yeast Saccharomyces cerevisiae is a dynamic trait, and efficient transitions between alternate haploid cell types allow the organism to access the advantageous diploid form. Mating identity is determined by cell type-specific transcriptional regulators, but these factors must be rapidly removed upon mating-type switching to allow the master regulators of the alternate state to establish a...

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PMID: 20351217
DOI: 10.1534/genetics.110.115907
PMCID: PMC2881132

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