Article
In pancreatic ductal adenocarcinoma blood concentrations of some organochlorine compounds and coffee intake are independently associated with KRAS mutations.
Mutagenesis - 1 Nov 2009
Porta Miquel, López Tomàs, Pumarega José, Jariod Manuel, Crous-Bou Marta, Marco Esther, Rifà Juli, Grimalt Joan O, Malats Núria, Real Francisco X
Abstract excerpt
While KRAS activation is a fundamental initiating event in the aetiopathogenesis of pancreatic ductal adenocarcinoma (PDA), environmental factors influencing the occurrence and persistence of KRAS mutations remain largely unknown. The objective was to test the hypothesis that in PDA there are aet...
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