Article
Donor clara cell secretory protein polymorphism is a risk factor for bronchiolitis obliterans syndrome after lung transplantation.
Transplantation - 27 Sept 2012
Bourdin Arnaud, Mifsud Nicole A, Chanez Brice, McLean Catriona, Chanez Pascal, Snell Greg, Kotsimbos Tom C
Abstract excerpt
BACKGROUND: We hypothesized that a reduced potential for bronchiolar stem-cell (Clara cell)-related repair in the setting of an ever-present risk of small airway injury would increase the risk of bronchiolitis obliterans syndrome (BOS). METHOD: CCSP A38G gene polymorphism was assessed in both lung donors and recipients in a longitudinal study cohort of 63 consecutive lung transplant recipients (LTR) with a median...
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