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Article

Polymorphism +17 C/G in matrix metalloprotease MMP8 decreases lung cancer risk.

BMC cancer - 19 Dec 2008

González-Arriaga Patricia, López-Cima M Felicitas, Fernández-Somoano Ana, Pascual Teresa, Marrón Manuel G, Puente Xose S, Tardón Adonina

Abstract excerpt

BACKGROUND: Matrix metalloproteases (MMPs) constitute a family of enzymes capable of degrading different components of the extracellular matrix and are implicated in the invasion of tumor cells through the basement membrane. Polymorphisms in MMP genes may result in changes in the expression of MMPs being associated with the development and progression of cancer. We have investigated the association between three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19094243
DOI: 10.1186/1471-2407-8-378
PMCID: PMC2628929

Genes

MMP8
MMP1
MMP13

Provenance

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