Article
Mitotic inter-homologue junctions accumulate at damaged DNA replication forks in recQ mutants.
DNA repair - 4 Jun 2010
Carotenuto Walter, Liberi Giordano
Abstract excerpt
Mitotic homologous recombination is utilised to repair DNA breaks using either sister chromatids or homologous chromosomes as templates. Because sister chromatids are identical, exchanges between sister chromatids have no consequences for the maintenance of genomic integrity unless they involve repetitive DNA sequences. Conversely, homologous chromosomes might differ in genetic content, and exchanges between...
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