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Article

Effect of fenofibrate therapy and ABCA1 polymorphisms on high-density lipoprotein subclasses in the Genetics of Lipid Lowering Drugs and Diet Network.

Molecular genetics and metabolism - 1 Jun 2010

Tsai Michael Y, Ordovas Jose M, Li Na, Straka Robert J, Hanson Naomi Q, Arends Valerie L, Arnett Donna

Abstract excerpt

BACKGROUND: Previous studies have shown that ATP-binding cassette transporter 1 (ABCA1) polymorphisms associated with increased ABCA1 expression result in increased small HDL (high-density lipoprotein) subclass particle concentration. This study examines the effect of treatment with fenofibrate, a drug known to bind peroxisome proliferator-activated receptor alpha (PPARalpha) which increases the expression of...

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Share to ATP Binding Cassette Transporter 1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholesterol, HDL

Share to Hypolipidemic Agents

Share to Lipoproteins, HDL

Share to Polymorphism, Genetic

Share to Polymorphism, Single Nucleotide

Share to PPAR alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 20346718
DOI: 10.1016/j.ymgme.2010.03.001
PMCID: PMC3598593

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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