Article
Effects of fenofibrate on plasma oxidized LDL and 8-isoprostane in a sub-cohort of GOLDN participants.
Atherosclerosis - 1 Feb 2011
Dong Yan, Steffen Brian T, Cao Jing, Tsai Alexander K, Ordovas Jose, Straka Robert, Zhou Xia, Kabagambe Edmond, Hanson Naomi Q, Arnett Donna, Tsai Michael Y
Abstract excerpt
BACKGROUND: Fenofibrate significantly reduces circulating triglyceride (TG) concentrations, particularly in individuals with elevated levels. The purpose of the current study was to determine whether fenofibrate treatment reduces markers of oxidative stress, oxidized low density lipoprotein (ox-LDL) and 8-isoprostane (8-isoP), in a manner similar to TG where those with the highest levels show the greatest...
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