Article
Pharmacogenetic association of the APOA1/C3/A4/A5 gene cluster and lipid responses to fenofibrate: the genetics of lipid-lowering drugs and diet network study.
Pharmacogenetics and genomics - 1 Feb 2009
Liu Yongjun, Ordovas Jose M, Gao Guimin, Province Michael, Straka Robert J, Tsai Michael Y, Lai Chao-Qiang, Zhang Kui, Borecki Ingrid, Hixson James E, Allison David B, Arnett Donna K
Abstract excerpt
BACKGROUND: The apolipoproteins (APOA1/C3/A4/A5) are key components in modulating lipoprotein metabolism. It is unknown whether variants at the APOA1/C3/A4/A5 gene cluster are associated with lipid response to pharmacologic intervention. METHODS AND RESULTS: Plasma triglycerides (TGs) and high-de...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
