Cell Death of Streptococcus mutans Induced by a Quorum-Sensing Peptide Occurs via a Conserved Streptococcal Autolysin

Abstract excerpt

Streptococcus mutans, a member of the human indigenous oral microbiome, produces a quorum-sensing peptide called the competence-stimulating peptide (CSP) pheromone. We previously demonstrated that S. mutans expresses its CSP pheromone under specific stresses and responds to high levels of CSP by inducing cell death in a fraction of the bacterial population. Streptococci lack the classical SOS response, and the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bacterial biofilms and quorum sensing
• Share to Oral microbiology and periodontitis research
• Share to Streptococcal Infections and Treatments