Article
Sialylation of integrin beta1 is involved in radiation-induced adhesion and migration in human colon cancer cells.
International journal of radiation oncology, biology, physics - 1 Apr 2010
Lee Minyoung, Lee Hae-June, Seo Woo Duck, Park Ki Hun, Lee Yun-Sil
Abstract excerpt
PURPOSE: Previously, we reported that radiation-induced ST6 Gal I gene expression was responsible for an increase of integrin beta1 sialylation. In this study, we have further investigated the function of radiation-mediated integrin beta1 sialylation in colon cancer cells. METHODS AND MATERIALS: We performed Western blotting and lectin affinity assay to analyze the expression and level of sialylated integrin...
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