Article
Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat.
Journal of virology - 1 Jun 1991
Cooney A J, Tsai S Y, O'Malley B W, Tsai M J
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR) contains a negative regulatory element (NRE) which downregulates the rate of LTR-directed transcription and HIV-1 replication. Within the NRE is a GGTCA palindrome, which binds a possible member of the steroid/thyroid horm...
Topics
- Base Sequence
- Binding Sites
- COUP Transcription Factor I
- DNA-Binding Proteins
- Genetic Variation
- HIV-1
- HeLa Cells
- Humans
- Molecular Sequence Data
- Polymorphism, Genetic
- Promoter Regions, Genetic
- Receptors, Thyroid Hormone
- Repetitive Sequences, Nucleic Acid
- Transcription Factors