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Article

Interferon regulatory factors (IRFs) repress transcription of the chicken ovalbumin gene.

Gene - 15 Jun 2009

Dougherty Dawne C, Park Hyi-Man, Sanders Michel M

Abstract excerpt

Although the ovalbumin (Ov) gene has served as a model to study tissue-specific, steroid hormone-induced gene expression in vertebrates for decades, the mechanisms responsible for regulating this gene remain elusive. Ov is repressed in non-oviduct tissue and in estrogen-deprived oviduct by a strong repressor site located from -130 to -100 and designated CAR for COUP-TF adjacent repressor. The goal of this study...

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Source

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Identifiers

PMID: 19341784
DOI: 10.1016/j.gene.2009.03.016
PMCID: PMC2749989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon regulatory factors (IRFs) repress transcription of the chicken ovalbumin gene.PMID 19341784Read ↗

The COUP-adjacent repressor (CAR) element participates in the tissue-specific expression of the ovalbumin gene.Semantic proximity Read ↗

A protein with a binding specificity similar to NF-kappa B binds to a steroid-dependent regulatory element in the ovalbumin gene.Semantic proximity Read ↗

Molecular mechanism of chicken ovalbumin upstream promoter-transcription factor (COUP-TF) actionsSemantic proximity Read ↗

DNA binding and transcription activation by chicken interferon regulatory factor-3 (chIRF-3).Semantic proximity Read ↗

Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin upstream promoter transcription factor I.Semantic proximity Read ↗

clRF-3, a new member of the interferon regulatory factor (IRF) family that is rapidly and transiently induced by dsRNASemantic proximity Read ↗

Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription.Semantic proximity Read ↗

Sequence and Expression Analysis of Interferon Regulatory Factor 10 (IRF10) in Three Diverse Teleost Fish Reveals Its Role in Antiviral DefenseSemantic proximity Read ↗

The zinc finger/homeodomain protein deltaEF1 mediates estrogen-specific induction of the ovalbumin gene.Semantic proximity Read ↗

Chicken Ovalbumin Upstream Promoter Transcription Factor (COUP-TF) Dimers Bind to Different GGTCA Response Elements, Allowing COUP-TF To Repress Hormonal Induction of the Vitamin D<sub>3</sub>, Thyroid Hormone, and Retinoic Acid ReceptorsSemantic proximity Read ↗

Identification of the novel player deltaEF1 in estrogen transcriptional cascades.Semantic proximity Read ↗

The steroid-dependent regulatory element in the ovalbumin gene does not function as a typical steroid response element.Semantic proximity Read ↗

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