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Article

Role of Radiation-induced TGF-beta Signaling in Cancer Therapy

10 Feb 2009

Abstract excerpt

TGF-β signaling regulates several different biological processes involving cell-growth, differentiation, apoptosis, motility, angiogenesis, epithelial mesenchymal transition and extracellular matrix production that affects embryonic development and pathogenesis of various diseases, including cancer, its effects depending on the cellular context and physiological environment. Growth suppression mediated by TGF-β...

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Identifiers

PMID: 20336170
DOI: 10.4255/mcpharmacol.09.06

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