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Article

Whole genome sequencing and novel candidate genes for CAKUT and altered nephrogenesis in the HSRA rat.

Physiological genomics - 1 Jan 2020

Showmaker Kurt C, Cobb Meredith B, Johnson Ashley C, Yang Wenyu, Garrett Michael R

Abstract excerpt

The HSRA rat is a model of congenital abnormalities of the kidney and urogenital tract (CAKUT). Our laboratory has used this model to investigate the role of nephron number (functional unit of the kidney) in susceptibility to develop kidney disease as 50-75% offspring are born with a single kidney (HSRA-S), while 25-50% are born with two kidneys (HSRA-C). HSRA-S rats develop increased kidney injury and...

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Share to Chromosomes, Mammalian
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-kit

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Source

Open in PubMed Open full text

Identifiers

PMID: 31841396
DOI: 10.1152/physiolgenomics.00112.2019
PMCID: PMC6985787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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