Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PathWave: discovering patterns of differentially regulated enzymes in metabolic pathways

24 Mar 2010

Abstract excerpt

MOTIVATION: Gene expression profiling by microarrays or transcript sequencing enables observing the pathogenic function of tumors on a mesoscopic level. RESULTS: We investigated neuroblastoma tumors that clinically exhibit a very heterogeneous course ranging from rapid growth with fatal outcome to spontaneous regression and detected regulatory oncogenetic shifts in their metabolic networks. In contrast to common...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bioinformatics and Genomic Networks
Share to Cell Image Analysis Techniques
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20335275
DOI: 10.1093/bioinformatics/btq113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PathWave: discovering patterns of differentially regulated enzymes in metabolic pathwaysPMID 20335275Read ↗

Activated Metabolic Transcriptional Program in Tumor Cells from HepatoblastomaSemantic proximity Read ↗

Analyzing the regulation of metabolic pathways in human breast cancerSemantic proximity Read ↗

Pan-cancer analysis of the metabolic reaction networkSemantic proximity Read ↗

MYCN Amplifications and Metabolic Rewiring in NeuroblastomaSemantic proximity Read ↗

datadrivenhypothesis.org: A resource for metabolic gene discovery through integrated pathway co-essentiality mappingSemantic proximity Read ↗

Discovery of multi-state gene cluster switches determining the adaptive mitochondrial and metabolic landscape of breast cancerSemantic proximity Read ↗

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinomaSemantic proximity Read ↗

A new genome-scale model enables prediction of cancer metabolic dependenciesSemantic proximity Read ↗

MaREA: Metabolic feature extraction, enrichment and visualization of RNAseq dataSemantic proximity Read ↗

The integrative metabolomic-transcriptomic landscape of glioblastome multiformeSemantic proximity Read ↗

Comparison of different computational frameworks for metabolic modeling from single-cell transcriptomics data in glioblastomaSemantic proximity Read ↗

Towards Decoding the Metabolic Plasticity in Cancer: Coupling of Gene Regulation and Metabolic PathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.