Article

MaREA: Metabolic feature extraction, enrichment and visualization of RNAseq data

2018-01-16

Abstract excerpt

The characterization of the metabolic deregulations that distinguish cancer phenotypes, and which might be effectively targeted by ad-hoc strategies, is a key open challenge. To this end, we here introduce MaREA (Metabolic Reaction Enrichment Analysis), a computational pipeline that processes cross-sectional RNAseq data to identify the metabolic reactions that are significantly up-/ down-regulated in different s...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9728de97-eb95-5c40-bb02-f3a9c45fd832
DOI: 10.1101/248724

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MaREA: Metabolic feature extraction, enrichment and visualization of RNAseq dataDOI 10.1101/248724Read

Cancer metabolic subtypes and their association with molecular and clinical featuresSemantic proximity Read

A Pan-Cancer Atlas of Metabolic Regulatory Circuitries Integrating Multi-Omic, Immune, and Clinical DimensionsSemantic proximity Read

RMetD2: a tool for integration of relative transcriptomics data into Genome-scale metabolic modelsSemantic proximity Read

Robust Metabolic Transcriptional Components in 34,494 Patient-Derived Samples and Cell LinesSemantic proximity Read

piTracer - Automatic reconstruction of molecular cascades for the identification of synergistic drug targetsSemantic proximity Read

A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulationSemantic proximity Read

Identifying personalized metabolic signatures in breast cancerSemantic proximity Read

Viime-Path: An Interactive Metabolic Pathway Generation Tool for Metabolomics Data AnalysisSemantic proximity Read

Network-aware reaction pattern recognition reveals regulatory signatures of mitochondrial dysfunctionSemantic proximity Read

Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway modelsSemantic proximity Read

PhenoMultiOmics: an enzymatic reaction inferred multi-omics network visualization web serverSemantic proximity Read

Low-dimensional representations of genome-scale metabolismSemantic proximity Read