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MYCN Amplifications and Metabolic Rewiring in Neuroblastoma

29 Sept 2023

Abstract excerpt

Cancer is a disease caused by (epi)genomic and gene expression abnormalities and characterized by metabolic phenotypes that are substantially different from the normal phenotypes of the tissues of origin. Metabolic reprogramming is one of the key features of tumors, including those established in the human nervous system. In this work, we emphasize a well-known cancerous genomic alteration: the amplification of...

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PMID: 37835497
DOI: 10.3390/cancers15194803

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