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Article

A Combination of Independent Transcriptional Regulators Shapes Bacterial Virulence Gene Expression during Infection

18 Mar 2010

Abstract excerpt

Transcriptional regulatory networks are fundamental to how microbes alter gene expression in response to environmental stimuli, thereby playing a critical role in bacterial pathogenesis. However, understanding how bacterial transcriptional regulatory networks function during host-pathogen interaction is limited. Recent studies in group A Streptococcus (GAS) suggested that the transcriptional regulator catabolite...

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PMID: 20333240
DOI: 10.1371/journal.ppat.1000817

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