Article
Allele-specific expression assays using Solexa.
BMC genomics - 9 Sept 2009
Main Bradley J, Bickel Ryan D, McIntyre Lauren M, Graze Rita M, Calabrese Peter P, Nuzhdin Sergey V
Abstract excerpt
BACKGROUND: Allele-specific expression (ASE) assays can be used to identify cis, trans, and cis-by-trans regulatory variation. Understanding the source of expression variation has important implications for disease susceptibility, phenotypic diversity, and adaptation. While ASE is commonly measured via relative fluorescence at a SNP, next generation sequencing provides an opportunity to measure ASE in an accurate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
