Article

Multigenic Control of Drug Response and Regulatory Decision-Making in Pharmacogenomics: The Need for an Upper-Bound Estimate of Genetic Contributions.

2005-03-01

Abstract excerpt

Nature or nurture? To what extent genetics play a role in drug efficacy and safety? These questions are not new. They are however gaining increasing prominence with the implementation of pharmacogenomics in various facets of medicine ranging from therapeutics, drug development and regulatory science to research funding decisions. For predisposition to common complex diseases, twin and family studies have been the...

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Literature Corpus work: 1fdaee0f-ee3e-58f1-92d9-5b0345705a41
DOI: 10.2174/1570160053175027

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