Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.

doi:10.1007/s10549-010-0842-y

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.

Breast cancer research and treatment - 1 Nov 2010

Moorman Patricia G, Iversen Edwin S, Marcom P Kelly, Marks Jeffrey R, Wang Frances, Lee Eunjung, Ursin Giske, Rebbeck Timothy R, Domchek Susan M, Arun Banu, Susswein Lisa, Isaacs Claudine, Garber Judy E, Visvanathan Kala, Griffin Constance A, Sutphen Rebecca, Brzosowicz Jennifer, Gruber Stephen, Finkelstein Dianne M, Schildkraut Joellen M

Abstract excerpt

The incomplete penetrance of mutations in BRCA1 and BRCA2 suggests that some combination of environmental and genetic factors modifies the risk of breast cancer in mutation carriers. This study sought to identify possible interactions between established breast cancer risk factors and BRCA1 or BRCA2 mutations using a case-only study design. Breast cancer cases that had been tested for BRCA1 and BRCA2 mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA1 Protein

Share to BRCA2 Protein

Share to Linear Models

Share to Logistic Models

Share to Menarche

Share to Parity

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 20309627
DOI: 10.1007/s10549-010-0842-y
PMCID: PMC2925060

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis.PMID 20309627Read ↗

Modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: systematic review and meta-analysis.Semantic proximity Read ↗

Modifiers of breast and ovarian cancer risks for BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Inherited predisposition and breast cancer: modifiers of BRCA1/2-associated breast cancer risk.Semantic proximity Read ↗

Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers.Semantic proximity Read ↗

Alcohol Consumption, Cigarette Smoking, and Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Results from The BRCA1 and BRCA2 Cohort Consortium.Semantic proximity Read ↗

Fixed and modifiable risk factors for breast cancer.Semantic proximity Read ↗

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA).Semantic proximity Read ↗

BRCA1/2 carriers and endocrine risk modifiers.Semantic proximity Read ↗

FGFR2 intronic SNPs and breast cancer risk: associations with tumor characteristics and interactions with exogenous exposures and other known breast cancer risk factors.Semantic proximity Read ↗

"Other" breast cancer susceptibility genes: searching for more holy grail.Semantic proximity Read ↗

Reproductive factors and breast cancer risk among BRCA1 or BRCA2 mutation carriers: results from ten studies.Semantic proximity Read ↗

Breast cancer risk factors differ between Asian and white women with BRCA1/2 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.