Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriers.

Abstract excerpt

Germline mutations in BRCA1 and BRCA2 confer high risks of female breast and ovarian cancer. However, there is strong evidence that these risks are modified by other factors, including familial or genetic factors. Genome-wide association studies have identified several breast cancer genetic susceptibility variants in the general population that are also associated with breast cancer risk for mutation carriers....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Breast Neoplasms
• Share to BRCA2 gene
• Share to Genes, BRCA1