Article
In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant gram-negative bacilli.
Antimicrobial agents and chemotherapy - 1 Jun 2010
Page Malcolm G P, Dantier Clothilde, Desarbre Eric
Abstract excerpt
BAL30072 is a new monocyclic beta-lactam antibiotic belonging to the sulfactams. Its spectrum of activity against significant Gram-negative pathogens with beta-lactam-resistant phenotypes was evaluated and was compared with the activities of reference drugs, including aztreonam, ceftazidime, cefepime, meropenem, imipenem, and piperacillin-tazobactam. BAL30072 showed potent activity against multidrug-resistant...
Topics
- Acinetobacter
- Anti-Bacterial Agents
- Drug Resistance, Multiple, Bacterial
- Enterobacteriaceae
- Escherichia coli
- Escherichia coli Proteins
- Gram-Negative Bacteria
- Humans
- Microbial Sensitivity Tests
- Monobactams
- Mutation
- Penicillin-Binding Proteins
- Phenotype
- Pseudomonas aeruginosa
- Siderophores
- Thiazoles
- beta-Lactams