Article
A practical method for phenotypic detection of metallo-β-lactamase-producing Pseudomonas aeruginosa and Acinetobacter spp. using sulfamoyl heteroarylcarboxylic acids.
Journal of microbiological methods - 1 Oct 2025
Norizuki Chihiro, Arakawa Yoshichika, Wachino Jun-Ichi
Abstract excerpt
Phenotypic screening using subclass B1 metallo-β-lactamase (MBL)-specific sulfamoyl heteroarylcarboxylic acid inhibitors (2,5-dimethyl-4-sulfamoylfuran-3-carboxylic acid and 2,5-diethyl-1-methyl-4-sulfamoylpyrrole-3-carboxylic acid) showed high sensitivity and specificity for detecting MBL-producing Pseudomonas aeruginosa and Acinetobacter spp. This practical and cost-effective method may support routine...
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