Article
Outer membrane permeability of beta-lactamase inhibitors in Pseudomonas aeruginosa.
FEMS microbiology letters - 15 Jun 1995
Satake S, Nakae T
Abstract excerpt
Evaluation of four beta-lactamase inhibitors in terms of their outer membrane permeability in Pseudomonas aeruginosa revealed that sulbactam and tazobactam diffused most efficiently and equally well. That of BRL42715 appeared to be a factor of ten lower than that of the above two, but it showed the strongest beta-lactamase inhibitory activity. This is most likely due to its better beta-lactamase inactivating...
Topics
- Cell Membrane
- Cell Membrane Permeability
- Mutation
- Pseudomonas aeruginosa
- beta-Lactamase Inhibitors
- beta-Lactamases