Article
Common genetic variation, residential proximity to traffic exposure, and left ventricular mass: the multi-ethnic study of atherosclerosis.
Environmental health perspectives - 1 Jul 2010
Van Hee Victor C, Adar Sara D, Szpiro Adam A, Barr R Graham, Diez Roux Ana, Bluemke David A, Sheppard Lianne, Gill Edward A, Bahrami Hossein, Wassel Christina, Sale Michele M, Siscovick David S, Rotter Jerome I, Rich Stephen S, Kaufman Joel D
Abstract excerpt
BACKGROUND: Elevated left ventricular mass (LVM) is a strong predictor of negative cardiovascular outcomes, including heart failure, stroke, and sudden cardiac death. A relationship between close (< 50 m compared with > 150 m) residential proximity to major roadways and higher LVM has previously been described, but the mechanistic pathways that are involved in this relationship are not known. Understanding...
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