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Article

Interferon-alpha and interleukin-6 in SLE serum induce the differentiation and maturation of dendritic cells derived from CD34+ hematopoietic precursor cells.

Cytokine - 1 May 2010

Zhang Rong, Xing Meifen, Ji Xiaohui, Gu Lei, Yang Xiaofan, Wang Huijuan, Jiang Pengtao

Abstract excerpt

The objective of this study was to investigate the effects of the cytokines IFN-alpha, IL-6 and IL-10 present in the serum of systemic lupus erythematosus (SLE) patients on the differentiation and maturation of DCs derived from CD34(+) hematopoietic precursor cells (HPCs). CD34(+) HPCs cultured in SLE serum containing elevated levels of IFN-alpha or IL-6 differentiated into DCs showing an increased expression of...

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Source

Identifiers

PMID: 20303780
DOI: 10.1016/j.cyto.2010.02.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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