Article
The angiotensin converting enzyme D allele is an independent risk factor for early onset coronary artery disease.
Clinical biochemistry - 1 Oct 2010
Vaisi-Raygani Asad, Ghaneialvar Hori, Rahimi Zohreh, Nomani Hamid, Saidi Mohmadreza, Bahrehmand Fariborz, Vaisi-Raygani Aliakbar, Tavilani Haidar, Pourmotabbed Tayebeh
Abstract excerpt
OBJECTIVE: The role of angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism in early onset coronary artery disease age < 55years (ECAD) is controversial. The aim of this study was to further evaluate the role of this ACE(I/D) gene polymorphism on the risk of premature CAD in patients from western Iran. METHODS: The ACE(I/D) genotypes were detected by PCR-RFLP in 323 individuals...
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