Article
Identification of three developmentally controlled isoforms of human myosin heavy chains.
European journal of biochemistry - 20 Apr 1990
Bober E, Buchberger-Seidl A, Braun T, Singh S, Goedde H W, Arnold H H
Abstract excerpt
A set of cDNA clones coding for myosin heavy chains (MHC) was isolated from a human fetal skeletal muscle library. We have demonstrated by restriction mapping and nucleotide sequence analysis that the cDNAs represent three distinct transcripts, presumably the products of different genes. Furthermore, the pattern of mRNA expression indicates that the corresponding genes are regulated in a tissue-specific and...
Topics
- Adult
- Amino Acid Sequence
- Base Sequence
- Blotting, Northern
- Blotting, Southern
- Cloning, Molecular
- DNA
- Female
- Fetus
- Genetic Variation
- Genomic Library
- Humans