Article
The genetic basis of host resistance to Bacillus anthracis in inbred mice.
Veterinary microbiology - 1 Feb 1991
Shibaya M, Kubomichi M, Watanabe T
Abstract excerpt
Inbred mice of the C3H/He (resistant) and C57BL/6 (susceptible) strains and their hybrids were used in experiments to investigate the genetic regulation of host resistance to B. anthracis. The susceptibility of F1 mice to a standard spore suspension was similar to that of the resistant parent and not intermediate between values for the parent strains. There were no differences in mortality rate between F1 and...
Topics
- Animals
- Anthrax
- Genetic Predisposition to Disease
- Immunity, Innate
- Mice
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Rodent Diseases
