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Article

Impaired skin regeneration and remodeling after cutaneous injury and chemically induced hyperplasia in taps-transgenic mice.

The Journal of investigative dermatology - 1 Jul 2010

Hildenbrand Maike, Rhiemeier Verena, Hartenstein Bettina, Lahrmann Bernd, Grabe Niels, Angel Peter, Hess Jochen

Abstract excerpt

Recently, we identified an AP-1-dependent target gene in 12-O-tetradecanoylphorbol-13-acetate (TPA)-treated mouse back skin, which encodes a retroviral-like aspartic proteinase (Taps/Asprv1). Taps expression was detected almost exclusively in stratified epithelia of mouse embryos and adult tissues, and enhanced protein levels were present in several non-neoplastic human skin disorders, implicating a crucial role...

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Identifiers

PMID: 20237492
DOI: 10.1038/jid.2010.54

Genes

UBC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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