Article
Haplotype analysis of p53 polymorphisms: Arg72Pro, Ins16bp and G13964C in Tunisian patients with familial or sporadic breast cancer.
Cancer epidemiology - 1 Apr 2010
Trifa Fatma, Karray-Chouayekh Sondes, Mabrouk Imed, Baccouche Sami, Khabir Abdelmajid, Sellami-Boudawara Tahia, Gargouri Ali, Mokdad-Gargouri Raja
Abstract excerpt
BACKGROUND: The p53 polymorphisms have been extensively studied as putative breast cancer susceptibility variants. The present study was undertaken to investigate the association of p53 Arg72Pro, Ins16bp and G13964C polymorphisms and their haplotypes with breast cancer risk in Tunisian women. METHODS: Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) on 159...
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