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Article

Consanguinity Protecting Effect Against Breast Cancer among Tunisian Women: Analysis of BRCA1 Haplotypes.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015

Medimegh Imen, Troudi Wafa, Omrane Ines, Ayari Hajer, Uhrhummer Nancy, Majoul Hamdi, Benayed Farhat, Mezlini Amel, Bignon Yves-Jean, Sibille Catherine, Elgaaied Amel Benammar

Abstract excerpt

The purpose of this study is to assess the effect of consanguinity on breast cancer incidence in Tunisia. We conducted a case-control study to evaluate the involvement of heterozygote and homozygote haplotypes of BRCA1 gene SNPs according to consanguinity among 40 cases of familial breast cancer, 46 cases with sporadic breast cancer and 34 healthy controls. We showed significant difference in consanguinity rate...

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Identifiers

PMID: 25987085
DOI: 10.7314/apjcp.2015.16.9.4051

Genes

BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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