Article
Potential genetic risk factors in angiotensin-converting enzyme-inhibitor-induced angio-oedema.
British journal of clinical pharmacology - 1 Feb 2010
Bas Murat, Hoffmann Thomas K, Tiemann Bernd, Dao Vu Thao-Vi, Bantis Christos, Balz Vera, Schultz-Coulon Hans-Jürgen, Stark Thomas, Schuler Patrick, Greve Jens, Ivens Katrin, Bier Henning, Kojda Georg
Abstract excerpt
AIMS: The pathophysiology of angiotensin-converting enzyme inhibitor (ACEi)-induced angio-oedema remains unclear. We have investigated the impact of ACE insertion/deletion (I/D) polymorphism in combination with serum ACE activity as well as the bradykinin B2 receptor 2/3 and c.C181T polymorphisms...
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