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Article

Association of B2 receptor polymorphisms and ACE activity with ACE inhibitor-induced angioedema in black and mixed-race South Africans.

Journal of clinical hypertension (Greenwich, Conn.) - 1 Jun 2013

Moholisa Retsilisitsoe R, Rayner Brian R, Patricia Owen E, Schwager Sylva L U, Stark Joalice S, Badri Motassim, Cupido Clint L, Sturrock Edward D

Abstract excerpt

Angiotensin-converting enzyme (ACE) inhibitors are first-line therapy for the treatment of hypertension, congestive heart failure, and diabetic nephropathy. ACE inhibitors are associated with adverse side effects such as persistent dry cough (ACE-cough) and, rarely, life-threatening angioedema (ACE-AE). The authors investigated the influence of ACE I/D polymorphism in combination with serum ACE activity, B₂...

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Share to Angioedema
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23730990
DOI: 10.1111/jch.12104
PMCID: PMC8033847

Genes

ACE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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