Article
Anthropometric and bone-related biochemical factors are associated with different haplotypes of ANKH locus.
Annals of human biology - 1 Jan 2000
Korostishevsky Michael, Vistoropsky Yulia, Malkin Ida, Kobyliansky Eugene, Livshits Gregory
Abstract excerpt
BACKGROUND: The human homologue of the mouse progressive ankylosis (ANKH) gene is one of the key genetic factors involved in bone mineralization. Previous studies have shown that plasma levels of osteoprotegerin (OPG) and parathyroid hormone (PTH) are associated with the distal region of the ANKH gene, whereas skeletal size measurements are associated with the promoter region. AIM: The present study examines the...
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