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Article

Common membrane trafficking defects of disease-associated dynamin 2 mutations.

Traffic (Copenhagen, Denmark) - 1 Nov 2011

Liu Ya-Wen, Lukiyanchuk Vasyl, Schmid Sandra L

Abstract excerpt

Dynamin (Dyn) is a multidomain and multifunctional GTPase best known for its essential role in clathrin-mediated endocytosis (CME). Dyn2 mutations have been linked to two human diseases, centronuclear myopathy (CNM) and Charcot-Marie-Tooth (CMT) disease. Paradoxically, although Dyn2 is ubiquitous...

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Source

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Identifiers

PMID: 21762456
DOI: 10.1111/j.1600-0854.2011.01250.x
PMCID: PMC3188678

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21762456-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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Common membrane trafficking defects of disease-associated dynamin 2 mutations.PMID 21762456Read ↗

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Dynamin 2 mutations in Charcot-Marie-Tooth neuropathy highlight the importance of clathrin-mediated endocytosis in myelination.Semantic proximity Read ↗

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